SCXA antibody

Catalog No. ABIN7863385

The Mouse Monoclonal anti-SCXA antibody (Clone PCRP-SCXA-1D2) (ABIN7863385) specifically detects SCXA in FACS and IF. The antibody is reactive with Human samples.

Quick Overview for SCXA antibody (ABIN7863385)

Target: SCXA (Scleraxis (SCXA))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SCXA antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: PCRP-SCXA-1D2

Product Details anti-SCXA Antibody

Purpose: SCXA Antibody

Specificity: Transcription factors are proteins that bind DNA adjacent to genes and control the production of mRNA transcripts. Scleraxis (basic helix-loop-helix transcription factor scleraxis) is a 201 amino acid protein that dimerizes with another bHLH protein to initiate transcription. Scleraxis is known to play a role in formation of mesoderm and somite-derived chondrogenic lineages. Scleraxis localizes to the nucleus and contains one bHLH domain. bHLH transcription factors, in general, function in cellular differentiation, proliferation, and oncogene regulation. The gene encoding Scleraxis maps to human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that map to chromosome 8.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant full-length human SCXA protein

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for SCXA

Target: SCXA (Scleraxis (SCXA))

Alternative Name: SCXA

Background:

Basic helix loop helix transcription factor scleraxis, bHLHa41, bHLHa48, Class A basic helix-loop-helix protein 41, Class A basic helix-loop-helix protein 48, scleraxis homolog A, SCX, SCXB

HeLa or HepG2 cells.

Molecular Weight: 22kDa

Gene ID: 642658, 723088

UniProt: Q7RTU7