SNW1 antibody

Catalog No. ABIN7862100

The Mouse Monoclonal anti-SNW1 antibody is suitable to detect SNW1 in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for SNW1 antibody (ABIN7862100)

Target: SNW1 (SNW Domain Containing 1 (SNW1))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This SNW1 antibody is un-conjugated

Application: Flow Cytometry (FACS)

Clone: PCRP-SNW1-1C12

Product Details anti-SNW1 Antibody

Purpose: SNW1 Antibody

Specificity: Nuclear receptor coactivator NCOA62/SNW1 (Nuclear Protein SkiP, SKIIP ski-interacting protein) is a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also interact with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment of human SNW1 protein

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for SNW1

Target: SNW1 (SNW Domain Containing 1 (SNW1))

Alternative Name: SNW1

Background:

Bx42, NCoA-62, Prp45, PRPF45, SKIIP, SKIP

HeLa or U87 cells. General nuclear expression.

Molecular Weight: 61.49kDa

Gene ID: 22938, 25040

UniProt: Q13573

Pathways: Retinoic Acid Receptor Signaling Pathway