Suprabasin antibody

Catalog No. ABIN7862143

The Mouse Monoclonal anti-Suprabasin antibody (Clone SBSN-7965) (ABIN7862143) specifically detects Suprabasin in IHC. The antibody is reactive with Human samples.

Quick Overview for Suprabasin antibody (ABIN7862143)

Target: Suprabasin (SBSN)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Suprabasin antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: SBSN-7965

Product Details anti-Suprabasin Antibody

Purpose: Suprabasin (SBSN) (CALB1) Antibody

Specificity: Suprabasin (SBSN) is a 247 amino acid secreted protein that is upregulated in differentiating keratinocytes and is though to play a role in epidermal differentiation. Expressed in uterus, skin, thymus and esophagus, suprabasin is encoded by a gene that maps to human chromosome 19q13.12. Chromosome 19 consists of about 63 million bases with over 1,400 genes, making up over 2 % of human genomic DNA. Chromosome 19 is the genetic home for a number of immunoglobulin superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG families, and Fca receptors. Key genes for eye color and hair color also map to chromosome 19. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and Insulin-dependent diabetes have been linked to chromosome 19.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment of human SBSN protein (exact sequence is proprietary)

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for Suprabasin

Target: Suprabasin (SBSN)

Alternative Name: Suprabasin

Background:

HLAR698, Suprabasin, UNQ698

Human thymus|uterus or esophagus.

Molecular Weight: 61kDa

Gene ID: 374897, 433484

UniProt: Q6UWP8