Recombinant TFE3 antibody

Catalog No. ABIN7863962

The Rabbit Monoclonal anti-TFE3 antibody is suitable to detect TFE3 in samples from Human. It has been validated for IHC.

Quick Overview for Recombinant TFE3 antibody (ABIN7863962)

Target: TFE3 (Transcription Factor E3 (TFE3))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This TFE3 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: TFE3-6849R

Product Details anti-TFE3 Antibody

Purpose: Recombinant Transcription factor E3 / TFE3 (Transcription Factor) Antibody

Specificity: Transcription factor E3 (TFE3) belongs to the basic helix-loop-helix zipper transcription factor family.Ç 79oΩThe TFE3 gene is located on the short arm of the X chromosome, is expressed in various cells of the human body, and participates in the regulation of various genes.Ç 79oΩThe rearrangement of this gene is associated with a variety of tumors, and it is highly expressed in acinar soft tissue sarcoma with TFE3 fusion gene, Xp11.2 translocation/TFE3 gene fusion-related renal cell carcinoma, and in perivascular epithelioid cell tumors. positive expression.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant full-length human TFE3 protein

Isotype: IgG, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for TFE3

Target: TFE3 (Transcription Factor E3 (TFE3))

Alternative Name: Transcription factor E3

Background:

NBLST2, NBPhox, Neuroblastoma paired type homeobox protein, Paired mesoderm homeobox protein 2B, Paired-like homeobox 2B, PHOX2B homeodomain protein, PMX2B

MiT family translocated renal cell carcinoma. Ubiquitous mainly nuclear expression.

Molecular Weight: 62kDa

Gene ID: 7030, 249142

UniProt: P19532