ZBTB7B antibody

Catalog No. ABIN7863209

The Mouse Monoclonal anti-ZBTB7B antibody is suitable to detect ZBTB7B in samples from Human. It has been validated for WB, IF and FACS.

Quick Overview for ZBTB7B antibody (ABIN7863209)

Target: ZBTB7B (Zinc Finger and BTB Domain Containing 7B (ZBTB7B))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ZBTB7B antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: PCRP-ZBTB7B-1F7

Product Details anti-ZBTB7B Antibody

Purpose: ZBTB7B Antibody

Specificity: TH-POK (T-helper-inducing POZ/Kr ppel-like factor), also known as zinc finger protein 67 (ZFP67), zinc finger and BTB domain-containing protein 7B or Kr ppel-related zinc finger protein cKrox, is a 539 amino acid protein that contains one BTB (POZ) domain and four C2H2-type zinc fingers. Localized to the nucleus, TH-POK functions primarily as a key regulator of lineage commitment of immature T-cell precursors. Specifically, the presence of TH-POK directs positively selected thymocytes to the CD4 lineage, whereas its absence causes default development to the CD8 lineage. TH-POK also functions as a transcriptional repressor of various other genes, such as COL1A1, COL1A2 and Fibronectin.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant full-length human ZBTB7B protein

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for ZBTB7B

Target: ZBTB7B (Zinc Finger and BTB Domain Containing 7B (ZBTB7B))

Alternative Name: ZBTB7B

Background:

cKrox, hcKrox, T helper inducing POZ/Kruppel like factor, Th-POK, ThPOK, ZBTB15, ZBTB7B, ZFP67, Zinc finger and BTB domain containing 15, Zinc finger and BTB domain containing 7B, Zinc finger protein 67 homolog, Zinc finger protein 857B, Zinc finger protein ThPOK, ZNF857B

HeLa or HepG2 cells.

Molecular Weight: 58/80kDa

Gene ID: 51043, 729279

UniProt: O15156