ZBTB46 antibody

Catalog No. ABIN7862668

The Mouse Monoclonal anti-ZBTB46 antibody is suitable to detect ZBTB46 in samples from Human. It has been validated for WB, IHC, IF and FACS.

Quick Overview for ZBTB46 antibody (ABIN7862668)

Target: ZBTB46 (ZNF340) (Zinc Finger Protein 340 (ZNF340))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ZBTB46 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: PCRP-ZBTB46-2B8

Product Details anti-ZBTB46 Antibody

Purpose: ZBTB46 / BTBD4 / ZNF340 Antibody

Specificity: BTBD4 (BTB/POZ domain-containing protein 4), also known as zinc finger protein 340 (ZNF340) or zinc finger and BTB domain-containing protein 46 (ZBTB46), is a 589 amino acid protein that contains one BTB/POZ domain. The BTB/POZ domain mediates homomeric and heteromeric POZ-POZ inter- actions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this tran- scriptional repression is attenuated. This suggests that BTBD4 may play a role in transcription regulation.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant full-length human ZBTB46 protein

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for ZBTB46

Target: ZBTB46 (ZNF340) (Zinc Finger Protein 340 (ZNF340))

Alternative Name: ZBTB46

Background:

BTB/POZ domain containing protein 4, BTBD4, RINZF, Zinc finger and BTB domain containing protein 46, Zinc finger protein 340, ZNF340

brain or rectum. HeLa or U-2 OS cells., Human tonsil

Molecular Weight: 64kDa

Gene ID: 140685, 585028

UniProt: Q86UZ6