ZNF408 antibody

Catalog No. ABIN7862296

The Mouse Monoclonal anti-ZNF408 antibody (Clone PCRP-ZNF408-1E5) (ABIN7862296) specifically detects ZNF408 in WB and FACS. The antibody is reactive with Human samples.

Quick Overview for ZNF408 antibody (ABIN7862296)

Target: ZNF408 (Zinc Finger Protein 408 (ZNF408))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ZNF408 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: PCRP-ZNF408-1E5

Product Details anti-ZNF408 Antibody

Purpose: ZNF408 / PRDM17 (Transcription Factor) Antibody

Specificity: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Kr ppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. As a member of the Kr ppel C2H2-type zinc-finger protein family, ZNF396 (zinc finger protein 396), also known as PRDM17 (PR domain zinc finger protein 17), is a 720 amino acid nuclear protein that contains ten C2H2-type zinc fingers. The gene encoding ZNF408 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4 % of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant full-length human ZNF408 protein

Isotype: IgG2b

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for ZNF408

Target: ZNF408 (Zinc Finger Protein 408 (ZNF408))

Alternative Name: ZNF408

Background:

EVR6, PFM14, PR domain zinc finger protein 17 (PRDM17), RP72, Zinc finger protein 408 (ZNF408)

HeLa or Raji cells. Ubiquitious nuclear expression.

Molecular Weight: 118kDa

Gene ID: 79797, 60300

UniProt: Q9H9D4