ZHX3 antibody

Catalog No. ABIN7862816

The Mouse Monoclonal anti-ZHX3 antibody (Clone PCRP-ZHX3-1G3) (ABIN7862816) specifically detects ZHX3 in WB, ELISA, IHC, IF and FACS. The antibody is reactive with Human samples.

Quick Overview for ZHX3 antibody (ABIN7862816)

Target: ZHX3 (Zinc Fingers and Homeoboxes 3 (ZHX3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ZHX3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: PCRP-ZHX3-1G3

Product Details anti-ZHX3 Antibody

Purpose: ZHX3 (Transcriptional Repressor) Antibody

Specificity: Zinc-fingers and homeobox (ZHX) proteins are transcription factors that interact with the activation domain of the A subunit of nuclear factor-Y (NF-YA). ZHX1-3 are ubiquitously expressed proteins expressed in various tissues. They act as transcriptional repressors and localize to the nucleus. The ZHX proteins contain two Cys2-His2-type zinc-finger motifs and five homeodomains (HDs). These domains allow the ZHX proteins to form homodimers, but they can also form heterodimers with each other. However, this dimerization is not required for repressor activity. Hypermethylation-mediated silencing of ZHX2 is an epigenetic event involved in hepatocellular carcinoma (HCC).

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant full-length human ZHX3 protein

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for ZHX3

Target: ZHX3 (Zinc Fingers and Homeoboxes 3 (ZHX3))

Alternative Name: ZHX3

Background:

KIAA0395, TIX1, Triple homeobox protein 1, ZHX 3, Zhx3, Zinc finger and homeodomain protein 3, Zinc fingers and homeoboxes protein 3

brain or thyroid., Human kidney

Molecular Weight: 105kDa

Gene ID: 23051, 380133

UniProt: Q9H4I2