CCL18 antibody (AA 1-89)

Catalog No. ABIN7862351

This Mouse Monoclonal antibody specifically detects CCL18 in IHC. It exhibits reactivity toward Human.

Quick Overview for CCL18 antibody (AA 1-89) (ABIN7862351)

Target: CCL18 (Chemokine (C-C Motif) Ligand 18 (Pulmonary and Activation-Regulated) (CCL18))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CCL18 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: CCL18-3744

Product Details anti-CCL18 Antibody

Binding Specificity: AA 1-89

Purpose: CCL18 / C-C motif chemokine ligand 18 Antibody

Specificity: Chemokines are members of a superfamily of small inducible, secreted, proinflammatory cytokines. Members of the chemokine family exhibit 20 to 50 % homology in their predicted amino acid sequences and are divided into four subfamilies. In C-C (or b) subfamily, the first two cysteines are adjacent. C-C chemokines are chemoattractants and activators for monocytes and T cells. C-C subfamily members include macrophage inflammatory protein (MIP)-1a, MIP-1b, MIP-2, MIP-3a, MIP-3b, MIP-4, HCC-1, MIP-5 (or HCC-2), RANTES, MCP-1/2/3 (and the murine homologs JE and MARC), I-309, murine C10 and TCA3. MIP-4 is constituitively expressed in several normal tissues and is highly expressed in plasma.

Purification: 200ug/ml of Ab purified from rabbit anti-serum by Protein A.

Immunogen: Recombinant fragment (around aa1-89) of human CCL18 protein (exact sequence is proprietary)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Target Details for CCL18

Target: CCL18 (Chemokine (C-C Motif) Ligand 18 (Pulmonary and Activation-Regulated) (CCL18))

Alternative Name: CCL18

Background:

CC chemokine PARC Dendritic cell chemokine 1 (DC-CK1), Macrophage inflammatory protein 4 (MIP-4), Pulmonary and activation-regulated chemokine, Small-inducible cytokine A18

Human lung, lymph node, placenta or tonsil.

Molecular Weight: 7kDa

Gene ID: 6362, 504281

UniProt: P55774