CSTA antibody

Catalog No. ABIN7865505

This Mouse Monoclonal antibody specifically detects CSTA in IHC. It exhibits reactivity toward Human.

Quick Overview for CSTA antibody (ABIN7865505)

Target: CSTA (Cystatin A (Stefin A) (CSTA))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CSTA antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: MSVA-461M

Product Details anti-CSTA Antibody

Purpose: Cystatin A Antibody

Specificity: The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins, and kininogens. This gene encodes a stefin that functions as a cysteine protease inhibitor, forming tight complexes with papain and the cathepsins B, H, and L. The protein is one of the precursor proteins of cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. Stefins have been proposed as prognostic and diagnostic tools for cancer.

Purification: Ab produced in CHO cell mammalian-based expression system.

Immunogen: Recombinant full-length human CSTA protein

Isotype: IgG2c, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Expiry Date: 24 months

Target Details for CSTA

Target: CSTA (Cystatin A (Stefin A) (CSTA))

Alternative Name: Cystatin A

Background:

STF1, STFA, AREI, cstA, Stefin A

Skin: A strong nuclear and cytoplasmic Cystatin A immunostaining should be seen in the granular layer.

Molecular Weight: 11kDa

Gene ID: 1475, 518198

UniProt: P01040

Pathways: Response to Water Deprivation