FX (AA 190-270) antibody

Catalog No. ABIN7862458

The Rabbit Polyclonal anti-FX antibody (ABIN7862458) specifically detects FX in WB and ELISA. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for FX (AA 190-270) antibody (ABIN7862458)

Target: FX

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), ELISA

Product Details

Binding Specificity: AA 190-270

Purpose: Rabbit Anti-FX Polyclonal Antibody

Specificity: FX Polyclonal Antibody detects endogenous levels of FX protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the C-terminal region of human FX at AA range: 190-270

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,ELISA 1:20000,Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details

Target: FX

Background: TSTA3, SDR4E1, GDP-L-fucose synthase, GDP-4-keto-6-deoxy-D-mannose-3, 5-epimerase-4-reductase, Protein FX, Red cell NADP(H)-binding protein, Short-chain dehydrogenase/reductase family 4E member 1Tissue specific transplantation antigen P35B is a NADP (H)-binding protein. It catalyze the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-deoxymannose to GDP-L-fucose. GDP-L-fucose is the substrate of several fucosyltransferases involved in the expression of many glycoconjugates, including blood group ABH antigens and developmental adhesion antigens. Mutations in TSTA3 (tissue specific transplantation antigen P35B)may cause leukocyte adhesion deficiency, type II.

Molecular Weight: 40kD

Gene ID: 7264

UniProt: Q13630