GABRR2 antibody

Catalog No. ABIN7862528

This Rabbit Polyclonal antibody specifically detects GABRR2 in WB and ELISA. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for GABRR2 antibody (ABIN7862528)

Target: GABRR2 (gamma-aminobutyric Acid (GABA) Receptor, rho 2 (GABRR2))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GABRR2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-GABRR2 Antibody

Purpose: Rabbit Anti-GBRR2 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of GBRR2 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human GBRR2 protein

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for GABRR2

Target: GABRR2 (gamma-aminobutyric Acid (GABA) Receptor, rho 2 (GABRR2))

Alternative Name: GBRR2

Background: Gamma-aminobutyric acid receptor subunit rho-2, GABA(A) receptor subunit rho-2, GABA(C) receptorGamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA receptors, which are ligand-gated chloride channels. The protein encoded by this gene is a member of the rho subunit family and is a component of the GABA type A receptor complex. This gene exists on chromosome 6q next to the gene encoding the rho 1 subunit of the GABA type A receptor, in a region thought to be associated with susceptibility for psychiatric disorders and epilepsy. Polymorphisms in this gene may also be associated with alcohol dependence, and general cognitive ability. GABRR2 (Gamma-Aminobutyric Acid Type A Receptor Rho2 Subunit) is a Protein Coding gene. Diseases associated with GABRR2 include Alcohol Dependence and Rett Syndrome. Among its related pathways are GABAergic synapse and Ligand-gated ion channel transport.

Molecular Weight: 51kD

Gene ID: 2570

UniProt: P28476