gH antibody

Catalog No. ABIN7862529

The Rabbit Polyclonal anti-gH antibody is suitable to detect gH in samples from Human, Rat and Mouse. It has been validated for ELISA, IHC and IF.

Quick Overview for gH antibody (ABIN7862529)

Target: gH

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details

Purpose: Rabbit Anti-GH Polyclonal Antibody

Specificity: The antibody detects endogenous levels of GH

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human GH protein at AA range: 180-217

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-200,ELISA 1:10000-20000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details

Target: gH

Target Type: Viral Protein

Background: Somatotropin, Growth hormone, GH, GH-N, Growth hormone 1, Pituitary growth hormone Growth hormone variant, GH-V, Growth hormone 2, Placenta-specific growth hormoneThe Growth Hormone 1 encoded by GH1 is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. GH1, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation, an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature.

Gene ID: 2688

UniProt: P01241, P01242