Liver Arginase antibody

Catalog No. ABIN7865561

This Mouse Monoclonal antibody specifically detects Liver Arginase in IHC. It exhibits reactivity toward Human.

Quick Overview for Liver Arginase antibody (ABIN7865561)

Target: Liver Arginase (ARG1) (Arginase, Liver (ARG1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Liver Arginase antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: IHC400

Product Details anti-Liver Arginase Antibody

Purpose: anti-Arginase-1 mouse monoclonal, IHC400, purified

Purification: affinity chromatography

Immunogen: Recombinant Human Arginase-1

Isotype: IgG2b

Application Details

Application Notes: Optional[ICC/IF_dilution]: 1:50-1:200 (microwave treatment recommended)

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Tris pH 7.3-7.7 with 1 % BSA and 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: store at 2 - 8 °C

Target Details for Liver Arginase

Target: Liver Arginase (ARG1) (Arginase, Liver (ARG1))

Alternative Name: Arginase-1

Background: Arginase-1, encoded by the ARG1 gene, is a cytosolic metalloenzyme expressed predominantly in hepatocytes. Arginase-1 plays a key role in the urea cycle by catalyzing the hydrolysis of arginine to ornithine and urea. Argininemia is an inherited autosomal recessive disorder characterized by a buildup of arginine and ammonia in the blood. Anti-Arginase-1 is highly specific for hepatocytes, and is therefore a sensitive and specific marker of benign and malignant hepatic tumours.

Pathways: Cellular Response to Molecule of Bacterial Origin