CCL16 antibody

Catalog No. ABIN7865613

The Mouse Monoclonal anti-CCL16 antibody is suitable to detect CCL16 in samples from Human. It has been validated for ELISA and IHC.

Quick Overview for CCL16 antibody (ABIN7865613)

Target: CCL16 (Chemokine (C-C Motif) Ligand 16 (CCL16))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CCL16 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Clone: LEC-14

Product Details anti-CCL16 Antibody

Purpose: anti-LEC / CCL16 / HCC4 mouse monoclonal, LEC-14, purified

Purification: affinity chromatography

Immunogen: recombinant human LEC

Isotype: IgG1 kappa

Application Details

Application Notes:

IHC-frozen_dilution: 1:50-1:100 (1-2 μg/mL)

elisa_dilution: assay dependent

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS with 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: store at 2 - 8 °C

Target Details for CCL16

Target: CCL16 (Chemokine (C-C Motif) Ligand 16 (CCL16))

Alternative Name: LEC / CCL16 / HCC4

Background: Liver Expressed Chemokine (LEC) is an 11 kDa inflammation related agent, known under many synonyms like Chemokine (C-C motif) Ligand 16 (CCL16), HCC4, NCC4, Monotactin-1 (MTN-1) etc. It is preferentially expressed and secreted by liver cells, but also found in spleen and thymus. It shows chemotactic activity towards activated lymphocytes and monocytes but not to neutrophils or resting lymphocytes. In monocytes, it is highly expressed after IL-10, LPS or IFN-gamma induction. It also shows potent myelosuppressive activity and suppresses proliferation of myeloid progenitor cells. LEC-receptors include CCR1, CCR2, CCR5 and CCR8. It is present in human serum in which it can be measured by ELISA. Positive control: Liver, spleen and thymus.