CGB antibody

Catalog No. ABIN7865642

This Mouse Monoclonal antibody specifically detects CGB in IHC. It exhibits reactivity toward Human.

Quick Overview for CGB antibody (ABIN7865642)

Target: CGB (Chorionic Gonadotropin, beta Polypeptide (CGB))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CGB antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: 5H4-E2

Product Details anti-CGB Antibody

Purpose: anti-hCG-beta mouse monoclonal,5H4-E2, purified

Purification: affinity chromatography

Immunogen: hCG beta, conjugated to various carrier proteins

Isotype: IgG1 kappa

Application Details

Application Notes:

IHC-paraffin_dilution: 1:50-1:100 (1-2 μg/mL)

IHC-frozen_dilution: 1:50-1:100 (1-2 μg/mL)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS with 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: store at 2 - 8 °C

Target Details for CGB

Target: CGB (Chorionic Gonadotropin, beta Polypeptide (CGB))

Alternative Name: hCG-beta

Background: 5H4-E2 reacts with hCG beta chain, which is specific for hCG. The alpha chain is identical among hCG, TSH, FSH and LH. While hCG is secreted in large quantities by normal trophoblasts, it is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. Besides trophoblastic tumors e.g. choriocarcinoma, large cell carcinoma, adenocarcinoma and squamous cell carcinoma of the lung are also positive in 90 % , 60 % and 20 % of cases respectively. In hCG producing tumors, including also certain testicular and embryonic carcinomas, the beta chain is produced in higher quantities than the alpha or dimeric chains. hCG expression by non-trophoblastic tumors may indicate aggressive behavior. Positive control: JAR or TT Cells. Placenta.