SALL4 antibody

Catalog No. ABIN7865730

The Mouse Monoclonal anti-SALL4 antibody is suitable to detect SALL4 in samples from Human. It has been validated for IHC.

Quick Overview for SALL4 antibody (ABIN7865730)

Target: SALL4 (Sal-Like 4 (SALL4))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This SALL4 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: IHC659

Product Details anti-SALL4 Antibody

Purpose: anti-SALL4 mouse monoclonal, IHC659, purified

Purification: affinity chromatography

Immunogen: Recombinant Human SALL4

Isotype: IgG1

Application Details

Application Notes: Optional[ICC/IF_dilution]: 1:50-1:200 (microwave treatment recommended)

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Tris pH 7.3-7.7 with 1 % BSA and 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: store at 2 - 8 °C

Target Details for SALL4

Target: SALL4 (Sal-Like 4 (SALL4))

Alternative Name: SALL4

Background: Sal-Like Protein 4 (SALL4) is a zinc finger transcription factor found in germ cells and human blood progenitor cells, with functional involvement in modulating Oct-4 to maintain embryonic stem cell pluripotency. SALL4 is a useful marker for acute myeloid leukemia, B-cell acute lymphocytic leukemia, intratubular germ cell neoplasia, seminomas/dysgerminomas, and yolk sac tumours (both pediatric and postpubertal). Anti-SALL4 is used to detect embryonal carcinomas, hepatocellular carcinoma (HCC), gliomas, ovarian primitive germcell tumours, choriocarcinomas, spermatogonia, teratoma, gastric cancer, breast cancer, and lung cancer. Expression of SALL4 is often associated with poor prognosis in HCC, and with metastasis in endometrial cancer, colorectal carcinoma, and esophageal squamous cell carcinoma.

Pathways: Stem Cell Maintenance, Tube Formation