CD37 antibody

Catalog No. ABIN7865743

The Mouse Monoclonal anti-CD37 antibody (Clone IPO-24) (ABIN7865743) specifically detects CD37 in FACS, IF, IHC and ICC. The antibody is reactive with Human samples.

Quick Overview for CD37 antibody (ABIN7865743)

Target: CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD37 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Clone: IPO-24

Product Details anti-CD37 Antibody

Purpose: anti-CD37 mouse monoclonal, IPO-24, purified

Purification: affinity chromatography

Immunogen: spleen cells of a patient with hairy cell leukemia

Isotype: IgG2b kappa

Application Details

Application Notes:

ICC/IF_dilution: 1:100-1:200 (0.5-1.0 μg/mL)

FACS_dilution: 0.5-1.0 μg/million cells in 0.1 ml

IHC-frozen_dilution: 1:50-1:100 (1-2 μg/mL)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS with 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: store at 2 - 8 °C

Target Details for CD37

Target: CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))

Alternative Name: CD37

Background: IPO-24 reacts with CD37, a B lineage restricted antigen, strongly expressed throughout B-cell ontogeny from pre B-cell until plasmablasts. Plasma cells are negative. IPO-24 reacts with human B-cell lines Daudi, Raji, Namalva, Ramos and CABIL, whereas T-cell lines CEM, Molt-4, Jurkat, MT-4, H9 and non-lymphoid cell lines MeWo and A-431 are negative. IPO-24 stains B-cell follicles and the most strongly labelled elements are mantle zone lymphoid cells. Neutrophils, macrophages, thymocytes and dendritic reticulum cells are negative. Positive control: Daudi, Raji, Namalva and CABIL cells, human tonsil or lymph node.

Pathways: Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response