TFE3 antibody

Catalog No. ABIN7865746

The Mouse Monoclonal anti-TFE3 antibody (Clone IHC672) (ABIN7865746) specifically detects TFE3 in IHC. The antibody is reactive with Human samples.

Quick Overview for TFE3 antibody (ABIN7865746)

Target: TFE3 (Transcription Factor E3 (TFE3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TFE3 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: IHC672

Product Details anti-TFE3 Antibody

Purpose: anti-TFE3 mouse monoclonal, IHC672, purified

Purification: affinity chromatography

Immunogen: Recombinant Human TFE3

Isotype: IgG1

Application Details

Application Notes: Optional[ICC/IF_dilution]: 1:50-1:200 (microwave treatment recommended)

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Tris pH 7.3-7.7 with 1 % BSA and 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: store at 2 - 8 °C

Target Details for TFE3

Target: TFE3 (Transcription Factor E3 (TFE3))

Alternative Name: TFE3

Background: Transcription Factor E3 (TFE3) is a transcription factor that binds to the MUE3-type E-box sequences involved in TGF-β signaling. Anti-TFE3 staining is the most sensitive and specific indicator of Xp11 translocation renal cell carcinomas. Since alveolar soft part sarcoma (ASPS) is characterized by a specific chromosomal rearrangement resulting in a chimeric transcription factor (ASPSCR1-TFE3), this TFE3 IVD antibody is also a useful diagnostic tool for recognizing ASPS.