TTF1 antibody

Catalog No. ABIN7865747

This Mouse Monoclonal antibody specifically detects TTF1 in IHC. It exhibits reactivity toward Human.

Quick Overview for TTF1 antibody (ABIN7865747)

Target: TTF1 (Transcription Termination Factor, RNA Polymerase I (TTF1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TTF1 antibody is un-conjugated

Application: Immunohistochemistry (IHC)

Clone: IHC414

Product Details anti-TTF1 Antibody

Purpose: anti-TTF-1 mouse monoclonal, IHC414, purified

Purification: affinity chromatography

Immunogen: TTF-1

Isotype: IgG2b kappa

Application Details

Application Notes: Optional[ICC/IF_dilution]: 1:50-1:200 (microwave treatment recommended)

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Tris pH 7.3-7.7 with 1 % BSA and 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: store at 2 - 8 °C

Target Details for TTF1

Target: TTF1 (Transcription Termination Factor, RNA Polymerase I (TTF1))

Alternative Name: TTF-1

Background: Thyroid Transcription Factor 1 (TTF-1) is present in diencephalon, lung, and thyroid. Anti-TTF-1 stains thyroid and thyroid-derived tumours, and is therefore used for distinguishing lung adenocarcinoma from germ cell tumours, malignant mesothelioma, and metastatic carcinomas from organs other than the thyroid. It is also useful for distinguishing small cell lung carcinoma from lymphoid infiltrates, and pulmonary from non-pulmonary adenocarcinomas in malignant effusions. The ability to distinguish between pulmonary and non-pulmonary adenocarcinomas is particularly useful in identifying tumours that have metastasized to the brain.

Pathways: Thyroid Hormone Synthesis, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour