Recombinant CD160 antibody (PE)

Catalog No. ABIN7867137

The Rabbit Chimeric anti-CD160 antibody is suitable to detect CD160 in samples from Human. It has been validated for FACS.

Quick Overview for Recombinant CD160 antibody (PE) (ABIN7867137)

Target: CD160

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Chimeric

Conjugate: This CD160 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: DMC270

Product Details anti-CD160 Antibody (PE)

Purpose: PE-conjugated Anti-CD160 antibody(DMC270), IgG1 Chimeric mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Isotype: IgG1

Application Details

Application Notes: Flow Cyt 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid PBS with 0.05 %  Proclin300, 1 % BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2°C-8°C for 6 months

Expiry Date: 6 months

Target Details for CD160

Target: CD160

Alternative Name: CD160

Background:

Synonyms: BY55, NK1, NK28

Target Background: CD160 is an 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD160 predicts a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 Molecule. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. RNA blot analysis revealed CD160 mRNAs of 1.5 and 1.6 kb whose expression was highly restricted to circulating NK and T cells, spleen and small intestine. Within NK cells CD160 is expressed by CD56dimCD16 cells whereas among circulating T cells its expression is mainly restricted to TCRgd bearing cells and to TCRab CD8brightCD95 CD56 CD28-CD27-cells. In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes. CD160 shows a broad specificity for binding to both classical and nonclassical MHC class I molecules.