CD86 antibody (PE)

Catalog No. ABIN7867187

This Rabbit Monoclonal antibody specifically detects CD86 in FACS. It exhibits reactivity toward Human.

Quick Overview for CD86 antibody (PE) (ABIN7867187)

Target: CD86

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CD86 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: DM84

Product Details anti-CD86 Antibody (PE)

Purpose: PE-conjugated Anti-B7-2 antibody(DM84), Rabbit mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Isotype: IgG

Application Details

Application Notes: Flow Cyt 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid PBS with 0.05 %  Proclin300, 1 % BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2°C-8°C for 6 months

Expiry Date: 6 months

Target Details for CD86

Target: CD86

Alternative Name: B7-2

Background:

Synonyms: CD86, B7-2, B70, CD28LG2, LAB72, MGC34413

Target Background: This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.

UniProt: P42081

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation