CXCR3 antibody (PE)

Catalog No. ABIN7867212

The Rabbit Monoclonal anti-CXCR3 antibody is suitable to detect CXCR3 in samples from Human. It has been validated for FACS.

Quick Overview for CXCR3 antibody (PE) (ABIN7867212)

Target: CXCR3 (Chemokine (C-X-C Motif) Receptor 3 (CXCR3))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CXCR3 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: DM208

Product Details anti-CXCR3 Antibody (PE)

Purpose: PE-conjugated Anti-CXCR3 antibody(DM208), Rabbit mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Isotype: IgG

Application Details

Application Notes: Flow Cyt 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid PBS with 0.05 %  Proclin300, 1 % BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2°C-8°C for 6 months

Expiry Date: 6 months

Target Details for CXCR3

Target: CXCR3 (Chemokine (C-X-C Motif) Receptor 3 (CXCR3))

Alternative Name: CXCR3

Background:

Synonyms: CD182, CD183, CKR-L2, CMKAR3, GPR9, IP10-R, Mig-R, MigR

Target Background: This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9:Mig (monokine induced by interferon-g), CXCL10:IP10 (interferon-g-inducible 10 kDa protein) and CXCL11:I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4:PF4 (PMID:12782716). [provided by RefSeq, Jun 2011]

UniProt: P49682