Recombinant CXCR4 antibody (PE)

Catalog No. ABIN7867213

The PE-conjugated Rabbit Chimeric anti-CXCR4 antibody (Clone DMC680) (ABIN7867213) specifically detects CXCR4 in FACS. The antibody is reactive with Human samples.

Quick Overview for Recombinant CXCR4 antibody (PE) (ABIN7867213)

Target: CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Chimeric

Conjugate: This CXCR4 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: DMC680

Product Details anti-CXCR4 Antibody (PE)

Purpose: PE-conjugated Anti-CXCR4 antibody(DMC680), IgG1 Chimeric mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Isotype: IgG1

Application Details

Application Notes: Flow Cyt 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid PBS with 0.05 %  Proclin300, 1 % BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2°C-8°C for 6 months

Expiry Date: 6 months

Target Details for CXCR4

Target: CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Alternative Name: CXCR4

Background:

Synonyms: CD184, D2S201E, FB22, HM89, HSY3RR, LAP-3, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3R, WHIM, WHIMS

Target Background: This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

UniProt: P61073

Pathways: Regulation of Cell Size, CXCR4-mediated Signaling Events