Recombinant F11R antibody (PE)

Catalog No. ABIN7867256

This Rabbit Chimeric antibody specifically detects F11R in FACS. It exhibits reactivity toward Human.

Quick Overview for Recombinant F11R antibody (PE) (ABIN7867256)

Target: F11R (F11 Receptor (F11R))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Chimeric

Conjugate: This F11R antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: DMC278

Product Details anti-F11R Antibody (PE)

Purpose: PE-conjugated Anti-JAM-A antibody(DMC278), IgG1 Chimeric mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Isotype: IgG1

Application Details

Application Notes: Flow Cyt 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Liquid PBS with 0.05 %  Proclin300, 1 % BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2°C-8°C for 6 months

Expiry Date: 6 months

Target Details for F11R

Target: F11R (F11 Receptor (F11R))

Alternative Name: JAM-A

Background:

Synonyms: CD321, JAM,JAM1, JAMA, JCAM, KAT, PAM-1

Target Background: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.

UniProt: Q9Y624

Pathways: Cell-Cell Junction Organization