TSH antibody

Catalog No. ABIN7867444

The Rabbit Monoclonal anti-TSH antibody (Clone EP254) (ABIN7867444) specifically detects TSH in IHC (fp). The antibody is reactive with Human samples.

Quick Overview for TSH antibody (ABIN7867444)

Target: TSH (Thyroid Stimulating Hormone (TSH))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This TSH antibody is un-conjugated

Application: Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone: EP254

Product Details anti-TSH Antibody

Purpose: Anti-TSH Rabbit Monoclonal Primary Antibody (Clone: EP254)

Isotype: IgG

Application Details

Application Notes:   immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500  

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Solution in Tris Buffer, pH 7.3-7.7, with 1 % BSA and

Storage: 4 °C

Storage Comment: Tightly closed. Recommended storage temperature 2 - 8 °C

Target Details for TSH

Target: TSH (Thyroid Stimulating Hormone (TSH))

Alternative Name: TSH

Background: Optional[Synonyms]: Thyroid-stimulating hormone (also known as TSH or thyrotropin) is a peptide hormone synthesized and secreted by thyrotrope cells in the anterior pituitary gland which regulate the endocrine function of the thyroid gland. TSH is a glycoprotein and consists of two subunits, the alpha and the beta subunit, which are non-covalently bound to one another. The alpha subunit of TSH is also present in two other pituitary glycoprotein hormones: Follicle stimulating hormone and luteinizing hormone and, in primates, in the placental hormone chorionic gonadotropin. Each of these hormones also has a unique beta subunit, which provides receptor specificity. In other words, TSH is composed of alpha subunit bound to the TSH beta subunit, and TSH associates only with its own receptor. Free alpha and beta subunits have essentially no biological activity. Anti-TSH reacts with TSH-producing cells (thyrotrophs), and is a useful marker in classification of pituitary tumors and the differential identification of primary and metastatic tumors in the pituitary gland.