Recombinant HIV-2 gp36 (AA 1-100) antibody

Catalog No. ABIN7867862

This Rabbit Monoclonal antibody specifically detects HIV-2 gp36 in ELISA, WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for Recombinant HIV-2 gp36 (AA 1-100) antibody (ABIN7867862)

Target: HIV-2 gp36

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: Un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: PDPN-7808R

Product Details

Binding Specificity: AA 1-100

Purpose: Gp36 Antibody / Glycoprotein 36 / Podoplanin

Purification: Protein A/G affinity

Immunogen: A recombinant partial protein sequence (within amino acids 1-100) from the human protein was used as the immunogen for the Gp36 antibody.

Isotype: IgG, kappa

Application Details

Application Notes: Optimal dilution of the Gp36 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Gp36 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details

Target: HIV-2 gp36

Alternative Name: Gp36

Target Type: Viral Protein

Background: It recognizes a muco-protein of 38-43 kDa, which is identified as Podoplanin (PDPN), also called Glycoprotein 36 (Gp36). It localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells. As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes. It is selectively expressed in lymphatic endotheliumas well as lymphoangiomas, Kaposi sarcomas, and in a subset of angiosarcomas with probable lymphatic differentiation. Recent studies have also shown podoplanin to be a highly sensitive and relatively specific marker for epithelioid mesothelioma. Therefore, it can be used in a panel to distinguish mesotheliomas or mesothelial cells from pulmonary carcinomas.

UniProt: Q86YL7