TKT antibody (AA 1-116)

Catalog No. ABIN7867989

The Mouse Monoclonal anti-TKT antibody is suitable to detect TKT in samples from Human, Rat and Mouse. It has been validated for WB, IF, FACS and IHC (p).

Quick Overview for TKT antibody (AA 1-116) (ABIN7867989)

Target: TKT (Transketolase (TKT))

Reactivity: Human, Rat, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This TKT antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 3E5-

Product Details anti-TKT Antibody

Binding Specificity: AA 1-116

Purpose: TKT Antibody / Transketolase

Purification: Affinity purified

Immunogen: A human recombinant partial protein (amino acids M1-A116) was used as the immunogen for the Transketolase antibody.

Isotype: IgG2a

Application Details

Application Notes: Optimal dilution of the Transketolase antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Transketolase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for TKT

Target: TKT (Transketolase (TKT))

Alternative Name: TKT

Background: Transketolase is a thiamine-dependent enzyme that links the pentose phosphate pathway with the glycolytic pathway. The pentose phosphate pathway, which is active in most tissues, provides sugar phosphates for intermediary biosynthesis, especially nucleotide metabolism, and generates the biosynthetic reducing power for the cell in the form of NADPH. Transketolase is directly involved in the branch of the pathway that channels excess sugar phosphates to glycolysis, enabling the production of NADPH to be maintained under different metabolic conditions. NADPH is critical for maintaining cerebral glutathione, and thus it is likely that transketolase plays an important role in brain metabolism.

UniProt: P29401