LGALS13 antibody (AA 1-139)

Catalog No. ABIN7868135

This Mouse Monoclonal antibody specifically detects LGALS13 in IHC (p). It exhibits reactivity toward Human.

Quick Overview for LGALS13 antibody (AA 1-139) (ABIN7868135)

Target: LGALS13 (Lectin, Galactoside-Binding, Soluble, 13 (LGALS13))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LGALS13 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: PP13-8897

Product Details anti-LGALS13 Antibody

Binding Specificity: AA 1-139

Purpose: Galectin 13 Antibody / LGALS13 / GAL13

Purification: Protein A/G affinity

Immunogen: A recombinant human Galectin-13 protein fragment (amino acids 1-139) was used as the immunogen for the Galectin 13 antibody.

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal dilution of the Galectin 13 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Galectin 13 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for LGALS13

Target: LGALS13 (Lectin, Galactoside-Binding, Soluble, 13 (LGALS13))

Alternative Name: Galectin 13

Background: It recognizes a 32 kDa protein, which is identified as homodimer of galectin-13 (also known as PP13). Galectins are a family of soluble beta-galactoside-binding lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. One such member, galectin-13, is a 139 amino acid protein that contains one galectin domain. Possessing lysophospholipase activity, galectin-13 exists as a disulfide-linked homodimer. Galectin-13 is suggested to have a developmental role in the placenta and may display immunobiological activity in feto-maternal blood-spaces. Screening for galectin-13 in maternal serum during the first trimester of pregnancy may serve as a diagnostic marker to predict preterm pre-eclampsia.

UniProt: Q9UHV8