SNAIL antibody (AA 1-170)

Catalog No. ABIN7868241

The Rabbit Polyclonal anti-SNAIL antibody is suitable to detect SNAIL in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and FACS.

Quick Overview for SNAIL antibody (AA 1-170) (ABIN7868241)

Target: SNAIL (SNAI1)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNAIL antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-SNAIL Antibody

Binding Specificity: AA 1-170

Purpose: SNAI1 Antibody / SNAIL

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids M1-K170) was used as the immunogen for the SNAI1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the SNAI1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the SNAI1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for SNAIL

Target: SNAIL (SNAI1)

Alternative Name: SNAI1

Background: The Drosophila embryonic protein SNAI1, commonly known as Snail, is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. And it is located in 16q24.3. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2. It is studied that SNAIL gene may show a role in recurrence of breast cancer by downregulating E-cadherin and inducing anepithelial to mesenchymal transition.

UniProt: O95863

Pathways: Negative Regulation of intrinsic apoptotic Signaling