ALAS2 antibody (AA 1-190)

Catalog No. ABIN7868330

This Rabbit Polyclonal antibody specifically detects ALAS2 in WB, ELISA, FACS and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for ALAS2 antibody (AA 1-190) (ABIN7868330)

Target: ALAS2 (Aminolevulinate, delta-, Synthase 2 (ALAS2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALAS2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF)

Product Details anti-ALAS2 Antibody

Binding Specificity: AA 1-190

Purpose: ALAS2 Antibody / ASB / 5-aminolevulinic acid synthase 2

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids M1-D190) was used as the immunogen for the ALAS2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the ALAS2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the ALAS2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for ALAS2

Target: ALAS2 (Aminolevulinate, delta-, Synthase 2 (ALAS2))

Alternative Name: ALAS2

Background: Delta-aminolevulinate synthase 2 also known as ALAS2 is a protein that in humans is encoded by the ALAS2 gene. The product of this gene specifies an erythroid-specific mitochondrially located enzyme. The encoded protein catalyzes the first step in the heme biosynthetic pathway. Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia. Alternatively spliced transcript variants encoding different isoforms have been identified.

UniProt: P22557

Pathways: Transition Metal Ion Homeostasis