CBX5 antibody (AA 1-191)

Catalog No. ABIN7868332

The Mouse Monoclonal anti-CBX5 antibody (Clone 8G6) (ABIN7868332) specifically detects CBX5 in WB, IF, IHC (p) and FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for CBX5 antibody (AA 1-191) (ABIN7868332)

Target: CBX5 (Chromobox Homolog 5 (CBX5))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This CBX5 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Clone: 8G6

Product Details anti-CBX5 Antibody

Binding Specificity: AA 1-191

Purpose: CBX5 Antibody / HP1A / HP1 alpha

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids M1-S191) was used as the immunogen for the CBX5 antibody.

Isotype: IgG2b

Application Details

Application Notes: Optimal dilution of the CBX5 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the CBX5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for CBX5

Target: CBX5 (Chromobox Homolog 5 (CBX5))

Alternative Name: CBX5

Background: This gene encodes the highly conserved nonhistone protein Chromobox protein homolog 5, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified.

UniProt: P45973