ITPA antibody (AA 1-194)

Catalog No. ABIN7868347

The Rabbit Polyclonal anti-ITPA antibody (ABIN7868347) specifically detects ITPA in WB, ELISA, FACS and IHC (p). The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for ITPA antibody (AA 1-194) (ABIN7868347)

Target: ITPA (Inosine Triphosphatase (ITPA))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ITPA antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-ITPA Antibody

Binding Specificity: AA 1-194

Purpose: ITPA Antibody / Inosine triphosphate pyrophosphatase / ITPase

Purification: Antigen affinity chromatography

Immunogen: An E.coli-derived human recombinant protein (amino acids M1-A194) was used as the immunogen for the ITPA antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the ITPA antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the ITPA Antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for ITPA

Target: ITPA (Inosine Triphosphatase (ITPA))

Alternative Name: ITPA

Background: Inosine triphosphate pyrophosphatase is an enzyme that in humans is encoded by the ITPA gene, by the rdgB gene in bacteria E.coli and the HAM1 gene in yeast S. cerevisiae, the protein is also encoded by some RNA viruses of the Potyviridae family. This gene encodes an inosine triphosphate pyrophosphohydrolase. The encoded protein hydrolyzes inosine triphosphate and deoxyinosine triphosphate to the monophosphate nucleotide and diphosphate. This protein, which is a member of the HAM1 NTPase protein family, is found in the cytoplasm and acts as a homodimer. Defects in the encoded protein can result in inosine triphosphate pyrophosphorylase deficiency which causes an accumulation of ITP in red blood cells. Alternate splicing results in multiple transcript variants.

UniProt: Q9BY32