NUMA1 antibody (AA 1-1954)

Catalog No. ABIN7868351

This Rabbit Polyclonal antibody specifically detects NUMA1 in WB, ELISA, IF, IHC (p) and FACS. It exhibits reactivity toward Human, Mouse, Rat and Monkey.

Quick Overview for NUMA1 antibody (AA 1-1954) (ABIN7868351)

Target: NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))

Reactivity: Human, Mouse, Rat, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NUMA1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-NUMA1 Antibody

Binding Specificity: AA 1-1954

Purpose: NUMA1 Antibody / Nuclear mitotic apparatus protein 1

Purification: Antigen affinity purified

Immunogen: An E.coli-derived human recombinant protein (M1-E1954) was used as the immunogen for the NUMA1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the NUMA1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the NUMA1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for NUMA1

Target: NUMA1 (Nuclear Mitotic Apparatus Protein 1 (NUMA1))

Alternative Name: NUMA1

Background: Nuclear mitotic apparatus protein 1 is a protein that in humans is encoded by the NUMA1 gene. This gene encodes a large protein that forms a structural component of the nuclear matrix. The encoded protein interacts with microtubules and plays a role in the formation and organization of the mitotic spindle during cell division. Chromosomal translocation of this gene with the RARA (retinoic acid receptor, alpha) gene on chromosome 17 have been detected in patients with acute promyelocytic leukemia. Alternative splicing results in multiple transcript variants.

UniProt: Q14980

Pathways: Caspase Cascade in Apoptosis, Regulation of Actin Filament Polymerization, M Phase