ADCY8 antibody (AA 1-200)

Catalog No. ABIN7868365

The Mouse Monoclonal anti-ADCY8 antibody (Clone ADCY8-7573) (ABIN7868365) specifically detects ADCY8 in IHC (p). The antibody is reactive with Human samples.

Quick Overview for ADCY8 antibody (AA 1-200) (ABIN7868365)

Target: ADCY8 (Adenylate Cyclase 8 (Brain) (ADCY8))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ADCY8 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: ADCY8-7573

Product Details anti-ADCY8 Antibody

Binding Specificity: AA 1-200

Purpose: ADCY8 Antibody / Adenylyl cyclase 8

Purification: Protein A/G affinity

Immunogen: A recombinant partial protein sequence (within amino acids 1-200) from the human protein was used as the immunogen for the ADCY8 antibody.

Isotype: IgG2, kappa

Application Details

Application Notes: Optimal dilution of the ADCY8 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the ADCY8 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for ADCY8

Target: ADCY8 (Adenylate Cyclase 8 (Brain) (ADCY8))

Alternative Name: ADCY8

Background: Adenylate cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. The enzymatic activity is under the control of several hormones, and different polypeptides participate in the transduction of the signal from the receptor to the catalytic moiety. Stimulatory or inhibitory receptors (Rs and Ri) interact with G proteins (Gs and Gi) that exhibit GTPase activity and they modulate the activity of the catalytic subunit of the adenylyl cyclase [provided by RefSeq, Jul 2008]

UniProt: P40145

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, cAMP Metabolic Process, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma