Recombinant CXCR5 antibody (AA 1-200)

Catalog No. ABIN7868451

The Rabbit Monoclonal anti-CXCR5 antibody is suitable to detect CXCR5 in samples from Human. It has been validated for IHC (p).

Quick Overview for Recombinant CXCR5 antibody (AA 1-200) (ABIN7868451)

Target: CXCR5 (Chemokine (C-X-C Motif) Receptor 5 (CXCR5))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CXCR5 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: CXCR5-8146R

Product Details anti-CXCR5 Antibody

Binding Specificity: AA 1-200

Purpose: CXCR5 Antibody / CD185 / BLR1 / MDR15

Purification: Protein A/G affinity

Immunogen: A recombinant partial protein sequence (within amino acids 1-200) from the human protein was used as the immunogen for the CXCR5 antibody.

Isotype: IgG, kappa

Application Details

Application Notes: Optimal dilution of the CXCR5 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the CXCR5 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for CXCR5

Target: CXCR5 (Chemokine (C-X-C Motif) Receptor 5 (CXCR5))

Alternative Name: CXCR5

Background: Burkitt s lymphoma receptor 1 (Blr1), also called CD185, CXCR5 and MDR15, is a lymphocyte specific chemokine receptor expressed at low levels in secondary lymphoid tissues and in defined structures of the cerebellum. The G protein-coupled receptor has significant homology to other chemokine receptors. Stimulation of Blr1 by its ligand, B-lymphocyte chemoattractant (BLC) results in an influx of calcium into the cell and the chemotaxis of the cell. Blr1 is required for B-cell migration into splenic and Peyer s patch follicles. BLC expression in Peyer s patches is highest in germinal centers, where B cells undergo somatic mutation and affinity maturation.

UniProt: P32302