FEV antibody (AA 1-200)

Catalog No. ABIN7868479

The Mouse Monoclonal anti-FEV antibody (Clone FEV-7311) (ABIN7868479) specifically detects FEV in IHC (p). The antibody is reactive with Human samples.

Quick Overview for FEV antibody (AA 1-200) (ABIN7868479)

Target: FEV (FEV (ETS Oncogene Family) (FEV))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FEV antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: FEV-7311

Product Details anti-FEV Antibody

Binding Specificity: AA 1-200

Purpose: PET-1 Antibody / PC12 ETS factor 1 / FEX

Purification: Protein A/G affinity

Immunogen: A recombinant partial protein sequence (within amino acids 1-200) from the human protein was used as the immunogen for the PET-1 antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the PET1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the PET1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for FEV

Target: FEV (FEV (ETS Oncogene Family) (FEV))

Alternative Name: PET-1

Background: Ets-1 is the prototype member of a family of genes identified on the basis of homology to the v-Ets oncogene isolated from the E26 erythroblastosis virus. This family of genes currently includes Ets-1, Ets-2, Erg-1-3, Elk-1, Elf-1, Elf-5, NERF, PU.1, PEA3, ERM, FEV, ER8l, Fli-1, TEL, Spi-B, ESE-1, ESE-3A, Net, ABT1 and ERF. Members of the Ets gene family exhibit varied patterns of tissue expression, and share a highly conserved carboxy terminal domain containing a sequence related to the SV40 large T antigen nuclear localization signal sequence. This conserved domain is essential for Ets-1 binding to DNA and is likely to be responsible for the DNA binding activity of all members of the Ets gene family. Several of these proteins have been shown to recognize similar motifs in DNA that share a centrally located 5'-GGAA-3' element.

UniProt: Q99581