HSD17B13 antibody (AA 1-200)

Catalog No. ABIN7868550

The Mouse Monoclonal anti-HSD17B13 antibody is suitable to detect HSD17B13 in samples from Human. It has been validated for IHC (p).

Quick Overview for HSD17B13 antibody (AA 1-200) (ABIN7868550)

Target: HSD17B13 (Hydroxysteroid (17-Beta) Dehydrogenase 13 (HSD17B13))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HSD17B13 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: HSD17B13-13109

Product Details anti-HSD17B13 Antibody

Binding Specificity: AA 1-200

Purpose: 17-beta-hydroxysteroid dehydrogenase 13 Antibody / HSD17B13 (azide and preservative free)

Purification: Protein G affinity

Immunogen: A portion of amino acids 1-200 of the human protein was used as the immunogen for the 17-beta-hydroxysteroid dehydrogenase 13 antibody.

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal dilution of the 17-beta-hydroxysteroid dehydrogenase 13 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the 17-beta-hydroxysteroid dehydrogenase 13 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for HSD17B13

Target: HSD17B13 (Hydroxysteroid (17-Beta) Dehydrogenase 13 (HSD17B13))

Alternative Name: 17-beta-hydroxysteroid dehydrogenase 13

Background: Hydroxysteroid 17-beta dehydrogenase 13 (HSD17B13) is an engyme in the liver that is associated with lipid droplets. It is encoded by the HSD17B13 gene in humans. HSD17B13 levels increase in patients with non-alcoholic fatty liver disease (NAFLD) and can enhance lipogenesis. However, some studies have shown that loss-of-function variants in HSD17B13 may protect against the progression of NAFLD to non-alcoholic steatohepatitis, fibrosis, and hepatocellular carcinoma.

UniProt: Q7Z5P4