HSD17B13 antibody (AA 1-200)

Catalog No. ABIN7868553

The Mouse Monoclonal anti-HSD17B13 antibody is suitable to detect HSD17B13 in samples from Human. It has been validated for IHC (p).

Quick Overview for HSD17B13 antibody (AA 1-200) (ABIN7868553)

Target: HSD17B13 (Hydroxysteroid (17-Beta) Dehydrogenase 13 (HSD17B13))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HSD17B13 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: HSD17B13-13108

Product Details anti-HSD17B13 Antibody

Binding Specificity: AA 1-200

Purpose: Hydroxysteroid 17-beta dehydrogenase 13 Antibody / HSD17B13

Purification: Protein G affinity

Immunogen: A portion of amino acids 1-200 of the human protein was used as the immunogen for the Hydroxysteroid 17-beta dehydrogenase 13 antibody.

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal dilution of the Hydroxysteroid 17-beta dehydrogenase 13 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles

Storage: -20 °C

Storage Comment: Aliquot the Hydroxysteroid 17-beta dehydrogenase 13 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for HSD17B13

Target: HSD17B13 (Hydroxysteroid (17-Beta) Dehydrogenase 13 (HSD17B13))

Alternative Name: Hydroxysteroid 17-beta dehydrogenase 13

Background: Hydroxysteroid 17-beta dehydrogenase 13 (HSD17B13) is an engyme in the liver that is associated with lipid droplets. It is encoded by the HSD17B13 gene in humans. HSD17B13 levels increase in patients with non-alcoholic fatty liver disease (NAFLD) and can enhance lipogenesis. However, some studies have shown that loss-of-function variants in HSD17B13 may protect against the progression of NAFLD to non-alcoholic steatohepatitis, fibrosis, and hepatocellular carcinoma.

UniProt: Q7Z5P4