HSD17B13 antibody (AA 1-200)

Catalog No. ABIN7868555

This Mouse Monoclonal antibody specifically detects HSD17B13 in IHC (p). It exhibits reactivity toward Human.

Quick Overview for HSD17B13 antibody (AA 1-200) (ABIN7868555)

Target: HSD17B13 (Hydroxysteroid (17-Beta) Dehydrogenase 13 (HSD17B13))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HSD17B13 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: HSD17B13-13106

Product Details anti-HSD17B13 Antibody

Binding Specificity: AA 1-200

Purpose: HSD17B13 Antibody / 17-beta-HSD 13

Purification: Protein G affinity

Immunogen: A portion of amino acids 1-200 of the human protein was used as the immunogen for the HSD17B13 antibody.

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal dilution of the HSD17B13 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the HSD17B13 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for HSD17B13

Target: HSD17B13 (Hydroxysteroid (17-Beta) Dehydrogenase 13 (HSD17B13))

Alternative Name: HSD17B13

Background: Hydroxysteroid 17-beta dehydrogenase 13 (HSD17B13) is an engyme in the liver that is associated with lipid droplets. It is encoded by the HSD17B13 gene in humans. HSD17B13 levels increase in patients with non-alcoholic fatty liver disease (NAFLD) and can enhance lipogenesis. However, some studies have shown that loss-of-function variants in HSD17B13 may protect against the progression of NAFLD to non-alcoholic steatohepatitis, fibrosis, and hepatocellular carcinoma.

UniProt: Q7Z5P4