HSD17B13 antibody (AA 1-200)

Catalog No. ABIN7868557

The Mouse Monoclonal anti-HSD17B13 antibody (Clone HSD17B13-13104) (ABIN7868557) specifically detects HSD17B13 in IHC (p). The antibody is reactive with Human samples.

Quick Overview for HSD17B13 antibody (AA 1-200) (ABIN7868557)

Target: HSD17B13 (Hydroxysteroid (17-Beta) Dehydrogenase 13 (HSD17B13))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HSD17B13 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: HSD17B13-13104

Product Details anti-HSD17B13 Antibody

Binding Specificity: AA 1-200

Purpose: 17-beta-HSD 13 Antibody / HSD17B13

Purification: Protein G affinity

Immunogen: A portion of amino acids 1-200 of the human protein was used as the immunogen for the 17-beta-HSD 13 antibody.

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal dilution of the 17-beta-HSD 13 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the 17-beta-HSD 13 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for HSD17B13

Target: HSD17B13 (Hydroxysteroid (17-Beta) Dehydrogenase 13 (HSD17B13))

Alternative Name: 17-beta-HSD 13

Background: Hydroxysteroid 17-beta dehydrogenase 13 (HSD17B13, 17-beta-HSD 13) is an enzyme in the liver that is associated with lipid droplets. It is encoded by the HSD17B13 gene in humans. HSD17B13 levels increase in patients with non-alcoholic fatty liver disease (NAFLD) and can enhance lipogenesis. However, some studies have shown that loss-of-function variants in HSD17B13 may protect against the progression of NAFLD to non-alcoholic steatohepatitis, fibrosis, and hepatocellular carcinoma.

UniProt: Q7Z5P4