Recombinant Keratin 72 antibody (AA 1-200)

Catalog No. ABIN7868626

The Rabbit Monoclonal anti-Keratin 72 antibody (Clone KRT6-8267R) (ABIN7868626) specifically detects Keratin 72 in IHC (p). The antibody is reactive with Human samples.

Quick Overview for Recombinant Keratin 72 antibody (AA 1-200) (ABIN7868626)

Target: Keratin 72 (KRT72)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Keratin 72 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: KRT6-8267R

Product Details anti-Keratin 72 Antibody

Binding Specificity: AA 1-200

Purpose: KRT6 Antibody / Cytokeratin 6 (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: A recombinant partial protein (within amino acids 1-200) from the human protein was used as the immunogen for the KRT6 antibody.

Isotype: IgG, kappa

Application Details

Application Notes: Optimal dilution of the KRT6 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the KRT6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Keratin 72

Target: Keratin 72 (KRT72)

Alternative Name: KRT6

Background: Cytokeratin 6 is an epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. This protein always paired with the type-I keratin K16. Cytokeratin 6 have been identified in epidermis only in samples from plantar glabrous skin while in hairy skin this keratin appeared to be absent in interfollicular epidermis but were clearly present in hair follicle outer root sheath, and this protein also consistently expressed in non-keratinizing stratified squamous epithelia. Among tumors, cytokeratin 6 is typically and strongly expressed in squamous cell carcinomas of different sites, preferentially in inner, maturing layers of the tumor cell nests. Cytokeratin 6 is always used with cytokeratin 5 and is a useful aid for classification of epithelioid mesotheliomas.

UniProt: P02538