CKAP5 antibody (AA 1-221)

Catalog No. ABIN7868849

This Rabbit Polyclonal antibody specifically detects CKAP5 in WB, ELISA, IF, ICC and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for CKAP5 antibody (AA 1-221) (ABIN7868849)

Target: CKAP5 (Cytoskeleton Associated Protein 5 (CKAP5))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CKAP5 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CKAP5 Antibody

Binding Specificity: AA 1-221

Purpose: Ch-TOG Antibody / CKAP5

Purification: Affinity purified

Immunogen: Amino acids M1-L221 from the human protein were used as the immunogen for the Ch-TOG antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Ch-TOG antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: Store the Ch-TOG antibody at -20oC.

Target Details for CKAP5

Target: CKAP5 (Cytoskeleton Associated Protein 5 (CKAP5))

Alternative Name: Ch-TOG

Background: Cytoskeleton-associated protein 5 is a microtubule-associated protein that in humans is encoded by the CKAP5 gene. It is mapped to 11p11.2. This gene encodes a cytoskeleton-associated protein which belongs to the TOG/XMAP215 family. The N-terminal half of this protein contains a microtubule-binding domain and the C-terminal half contains a KXGS motif for binding tubulin dimers. This protein has two distinct roles in spindle formation, it protects kinetochore microtubules from depolymerization and plays an essential role in centrosomal microtubule assembly. This protein may be necessary for the proper interaction of microtubules with the cell cortex for directional cell movement.

UniProt: Q14008

Pathways: M Phase