RGS18 antibody (AA 1-230)

Catalog No. ABIN7868879

This Rabbit Polyclonal antibody specifically detects RGS18 in ELISA, WB and FACS. It exhibits reactivity toward Human.

Quick Overview for RGS18 antibody (AA 1-230) (ABIN7868879)

Target: RGS18 (Regulator of G-Protein Signalling 18 (RGS18))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RGS18 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Flow Cytometry (FACS)

Product Details anti-RGS18 Antibody

Binding Specificity: AA 1-230

Purpose: RGS18 Antibody

Purification: Affinity purified

Immunogen: Recombinant human protein (amino acids M1-D230) was used as the immunogen for the RGS18 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the RGS18 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the RGS18 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for RGS18

Target: RGS18 (Regulator of G-Protein Signalling 18 (RGS18))

Alternative Name: RGS18

Background: Regulator of G-protein signaling 18 is a protein that in humans is encoded by the RGS18 gene. This gene encodes a member of the regulator of G-protein signaling family. This protein is contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

UniProt: Q9NS28

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling