MED7 antibody (AA 1-233)
Quick Overview for MED7 antibody (AA 1-233) (ABIN7868884)
Target
See all MED7 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1-233
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Purpose
- MED7 Antibody / Mediator of RNA polymerase II transcription subunit 7
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Purification
- Antigen affinity purified
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Immunogen
- Recombinant human protein (amino acids M1-P233) was used as the immunogen for the MED7 antibody.
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Isotype
- IgG
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Application Notes
- Optimal dilution of the MED7 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Storage
- 4 °C,-20 °C
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Storage Comment
- After reconstitution, the MED7 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- MED7 (Mediator Complex Subunit 7 (MED7))
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Alternative Name
- MED7
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Background
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MED7 (Mediator of RNA polymerase II transcription subunit 7) is a component of the Mediator complex, a multiprotein assembly that serves as a bridge between transcription factors and RNA polymerase II. MED7 plays a role in regulating transcription initiation, elongation, and co-activation of gene expression across diverse cellular processes.
MED7 is ubiquitously expressed and contributes to the regulation of genes involved in development, cell cycle progression, and differentiation. Dysregulation of Mediator subunits, including MED7, has been linked to transcriptional misregulation in cancer and developmental disorders, making it an important target in transcriptional biology research.
Using a high-quality MED7 antibody allows sensitive detection in applications such as western blot, immunohistochemistry, and chromatin immunoprecipitation. A MED7 antibody from NSJ Bioreagents ensures specificity and reproducibility for studies focused on transcriptional control, Mediator complex biology, and disease mechanisms. Selecting the right MED7 antibody is essential for generating consistent and meaningful data.
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UniProt
- O43513
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Pathways
- Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
Target
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