RBM9 antibody (AA 1-256)

Catalog No. ABIN7868987

This Rabbit Polyclonal antibody specifically detects RBM9 in WB, ELISA, IF, IHC (p) and FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for RBM9 antibody (AA 1-256) (ABIN7868987)

Target: RBM9 (RNA Binding Motif Protein 9 (RBM9))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RBM9 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-RBM9 Antibody

Binding Specificity: AA 1-256

Purpose: RBFOX2 Antibody / RNA binding protein fox-1 homolog 2 / RBM9

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids M1-Y256) was used as the immunogen for the RBFOX2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the RBFOX2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the RBFOX2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for RBM9

Target: RBM9 (RNA Binding Motif Protein 9 (RBM9))

Alternative Name: RBFOX2

Background: RNA binding motif protein 9 (RBM9), also known as Rbfox2, is a protein which in humans is encoded by the RBM9 gene. It is mapped to 22q12.3. This gene is one of several human genes similar to the C. elegans gene Fox-1. This gene encodes an RNA binding protein that is thought to be a key regulator of alternative exon splicing in the nervous system and other cell types. The protein binds to a conserved UGCAUG element found downstream of many alternatively spliced exons and promotes inclusion of the alternative exon in mature transcripts. The protein also interacts with the estrogen receptor 1 transcription factor and regulates estrogen receptor 1 transcriptional activity. Multiple transcript variants encoding different isoforms have been found for this gene.

UniProt: O43251

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Skeletal Muscle Fiber Development