RASD1 antibody (AA 1-281)

Catalog No. ABIN7869043

The Rabbit Polyclonal anti-RASD1 antibody (ABIN7869043) specifically detects RASD1 in WB, ELISA and FACS. The antibody is reactive with Mouse, Human and Rat samples.

Quick Overview for RASD1 antibody (AA 1-281) (ABIN7869043)

Target: RASD1 (RAS, Dexamethasone-Induced 1 (RASD1))

Reactivity: Mouse, Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RASD1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Product Details anti-RASD1 Antibody

Binding Specificity: AA 1-281

Purpose: Dexras1 Antibody / RASD1

Purification: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids M1-S281) was used as the immunogen for the Dexras1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Dexras1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Dexras1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for RASD1

Target: RASD1 (RAS, Dexamethasone-Induced 1 (RASD1))

Alternative Name: Dexras1

Background: Dexamethasone-induced Ras-related protein 1 (RASD1) is a protein that in humans is encoded by the RASD1 gene on chromosome 17. This gene encodes a member of the Ras superfamily of small GTPases and is induced by dexamethasone. The encoded protein is an activator of G-protein signaling and acts as a direct nucleotide exchange factor for Gi-Go proteins. This protein interacts with the neuronal nitric oxide adaptor protein CAPON, and a nuclear adaptor protein FE65, which interacts with the Alzheimer's disease amyloid precursor protein. This gene may play a role in dexamethasone-induced alterations in cell morphology, growth and cell-extracellular matrix interactions. Epigenetic inactivation of this gene is closely correlated with resistance to dexamethasone in multiple myeloma cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

UniProt: Q9Y272