EN1 antibody (AA 1-30)
Quick Overview for EN1 antibody (AA 1-30) (ABIN7869088)
Target
See all EN1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1-30
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Purpose
- Engrailed 1 Antibody / EN1
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Purification
- Antigen affinity purified
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Immunogen
- A portion of amino acids 1-30 from the human protein was used as the immunogen for the Engrailed 1 antibody.
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Isotype
- Ig Fraction
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Application Notes
- The stated application concentrations are suggested starting points. Titration of the Engrailed 1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot the Engrailed 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- EN1 (Engrailed Homeobox 1 (EN1))
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Alternative Name
- Engrailed 1
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Background
- Homeobox-containing genes are thought to have a role in controlling development. In Drosophila, the 'engrailed' (en) gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Different mutations in the mouse homologs, En1 and En2, produced different developmental defects that frequently are lethal. The human engrailed homologs 1 and 2 encode homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system.
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UniProt
- Q05925
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Pathways
- Dopaminergic Neurogenesis
Target
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