HDAC11 antibody (AA 1-30)

Catalog No. ABIN7869091

The Rabbit Polyclonal anti-HDAC11 antibody (ABIN7869091) specifically detects HDAC11 in WB and IHC (p). The antibody is reactive with Human and Mouse samples.

Quick Overview for HDAC11 antibody (AA 1-30) (ABIN7869091)

Target: HDAC11 (Histone Deacetylase 11 (HDAC11))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HDAC11 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-HDAC11 Antibody

Binding Specificity: AA 1-30

Purpose: HDAC11 Antibody

Purification: Purified

Immunogen: A portion of amino acids 1-30 from the human protein was used as the immunogen for the HDAC11 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the HDAC11 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the HDAC11 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for HDAC11

Target: HDAC11 (Histone Deacetylase 11 (HDAC11))

Alternative Name: HDAC11

Background: HDAC11 is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. The predominantly nuclear HDAC11, which interacts with HDAC6, is weakly expressed in most tissues, and strongly expressed in brain, heart, skeletal muscle, kidney and testis. Its activity is inhibited by trapoxin, a known histone deacetylase inhibitor.

UniProt: Q96DB2