TSEN34 antibody (AA 1-310)

Catalog No. ABIN7869177

The Rabbit Polyclonal anti-TSEN34 antibody is suitable to detect TSEN34 in samples from Human, Mouse and Rat. It has been validated for WB, IF and ELISA.

Quick Overview for TSEN34 antibody (AA 1-310) (ABIN7869177)

Target: TSEN34 (tRNA Splicing Endonuclease 34 Homolog (TSEN34))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TSEN34 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), ELISA

Product Details anti-TSEN34 Antibody

Binding Specificity: AA 1-310

Purpose: TSEN34 Antibody / tRNA-splicing endonuclease subunit Sen34

Purification: Antigen affinity purified

Immunogen: E. coli-derived recombinant human protein (amino acids M1-Q310) was used as the immunogen for the TSEN34 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the TSEN34 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the TSEN34 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for TSEN34

Target: TSEN34 (tRNA Splicing Endonuclease 34 Homolog (TSEN34))

Alternative Name: TSEN34

Background: TRNA-splicing endonuclease subunit Sen34 is an enzyme that in humans is encoded by the TSEN34 gene. This gene encodes a catalytic subunit of the tRNA splicing endonuclease, which catalyzes the removal of introns from precursor tRNAs. The endonuclease complex is also associated with a pre-mRNA 3-prime end processing factor. A mutation in this gene results in the neurological disorder pontocerebellar hypoplasia type 2. Multiple alternatively spliced variants, encoding the same protein, have been identified.

UniProt: Q9BSV6